Prof. Dr. Daniel Rauh Chemical Biology and Medicinal Chemistry
TU Dortmund University Otto-Hahn-Str. 4a 44227 Dortmund Phone: +49 (0) 231 755 7080 E-Mail: Daniel.rauh@tu-dortmund.de
Dr. Corinna Ottmann Phone: +49 (0) 231 755 8834 E-Mail: ddhd@tu-dortmund.de
Robotics Assisted Screening Platform for Efficient Ligand Discovery
The Robotics Assisted Screening Platform for Efficient Ligand Discovery (RASPELD) provides semi-automated high-end screening in the quest of identifying bioactive compounds for DrugDiscovery and Research.
Fluorescent Labels in Kinases
We developed a high-throughput screening technology that can discriminate for inhibitors, which stabilize inactive kinase conformations by binding within allosteric pockets in the kinase domain.
Fluorescent Labels in Nuclear Receptors
A direct binding assay that detects conformational changes in the estrogen receptor.
Flourescent Labels in Phosphatases
A novel binding assay capable of detecting ligands of an allosteric pocket of phosphatases.