Alexandros Pervanidis Receives Poster Award at the 18th Day of Chemistry

Alexandros Pervanidis, a second-year Ph.D. student, was awarded a poster prize for his innovative research at the 18th Annual Day of Chemistry in Dortmund, Germany. His work focuses on the structure-based design of isoform-selective covalent allosteric inhibitors (CAAIs) targeting Akt2 and Akt3 to further investigate their implication in cancer progression and metabolism. By elucidating the distinct roles of these isoforms and designing inhibitors that selectively bind to a unique allosteric pocket, this work aims to improve cancer treatments. His research on the design and synthesis of new probes offers the potential for more targeted therapies with fewer side effects than conventional inhibitors while advancing our understanding of Akt isoform functions.